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. Author manuscript; available in PMC: 2013 Jun 26.
Published in final edited form as: Cancer Res. 2011 May 17;71(14):5020–5029. doi: 10.1158/0008-5472.CAN-11-0908

Fig. 3. STAT3 is phosphorylated at multiple stages of pancreatic tumorigenesis.

Fig. 3

A, ADM and late-stage PanIN tissue from Pdx1-Cre; LSL-KRASG12D mice and PDAC tissue from Pdx1-Cre; LSL-KRASG12D; p53+/− mice were analyzed for the presence of P-STAT3 (green) by immunofluoresence with DAPI nuclear counterstain (blue). After image capture, slides were stained with hematoxylin and eosin (H&E). Arrows indicate regions of ADM. Normal pancreas is indicated by (N). B, higher magnification images of P-STAT3 staining (green) in ADM (upper half of image, A) or early-stage PanIN (lower half of image, P) lesions or in PDAC are shown.