The relaxivity of the nanoparticles.
Notes: (A) T2-weighted MR images of PEG-USPIO and LYVE-1-PEG-USPIO in agarose gel with various concentrations at 3.0 T MRI. (B) Graph of the R2 against the Fe concentration for PEG-USPIO and LYVE-1-PEG-USPIO. The relaxivity of PEG-USPIO was 608.32 mM−1s−1, the relaxivity of LYVE-1-PEG-USPIO was 185.48 mM−1s−1.
Abbreviations: LYVE-1-PEG-USPIO, lymphatic vessel endothelial hyaluronan receptor-1 binding polyethylene glycol-coated ultrasmall superparamagnetic iron oxide; MR, magnetic resonance; MRI, magnetic resonance imaging; PEG-USPIO, polyethylene glycol-coated ultrasmall superparamagnetic iron oxide.