Table 1. Identification of putative LmSTI1a-specific MHC II restricted peptides.
Strain | MHC IIhaplotype | LmSTIpeptide pool | Responding15-mer peptide | Position (aa) | Sequence | %IFN-γ+ CD4+ T cells |
C57Bl/6 | H-2b | 1 | p5 | 17–31 | GRYVEAVNYFSKAIQ | 0.526±0.159 |
p6 | 21–35 | EAVNYFSKAIQLDEQ | 0.266±0.120 | |||
C57Bl/6 | H-2b | 2 | p16 | 61–75 | DKCISIKPNWAKGYV | 0.315±0.198 |
p17 | 65–79 | SIKPNWAKGYVRRGA | 0.236±0.146 | |||
C57Bl/6 | H-2b | 8 | p88 | 348–362 | VEEAYIDPEIAKQKK | 3.052±0.982 |
p89 | 352–366 | YIDPEIAKQKKDEGN | 2.335±0.776 | |||
Balb/c | H-2d | 2 | p16 | 61–75 | DKCISIKPNWAKGYV | 0.390±0.103 |
p17 | 65–79 | SIKPNWAKGYVRRGA | 0.215±0.035 | |||
Balb/c | H-2d | 8 | p87 | 344–358 | HQKAVEEAYIDPEIA | 0.805±0.173 |
p88 | 348–362 | VEEAYIDPEIAKQKK | 1.012±0.366 |