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. 2013 Jun 26;8(6):e66902. doi: 10.1371/journal.pone.0066902

Table 4. The gene signature from the microarray dataset using SamR analysis.

ProbeSetID GeneSymbol log2FoldChange SamR-q-value(%) SamRposition DESeqPosition log2Ratio adjustedPvalue
209854 s at KLK2 3.84 0 1 15 3.18 5.77E-160
210339 s at KLK2 3.48 0 2 15 3.18 5.77E-160
205041 s at ORM1/ORM2 3.78 0 3 NA NA NA
211689 s at TMPRSS2 3.12 0 4 18 2.26 8.87E-130
222118 at CENPN 2.58 0 11 6 5.09 2.12E-295
217875 s at PMEPA1 2.38 0 13 142 2.99 1.4E-30
205862 at GREB1 2.36 0 14 1356 1.00 0.000149717
219049 at CSGALNACT1 2.21 0 15 1061 1.81 0.0000119
205102 at TMPRSS2 2.07 0 16 NA NA NA
204583 x at KLK3 1.96 0 20 31 1.81 1.14E-102
204582 s at KLK3 2.02 0 21 31 1.81 1.14E-102
209706 at NKX3-1 1.95 0 22 36 2.49 2.59E-90
219555 s at CENPN 1.93 0 29 6 5.09 2.12E-295
204560 at FKBP5 2.04 0 30 2 5.08 0
203196 at ABCC4 1.69 0 33 23 2.85 5.94E-117
221584 s at KCNMA1 1.57 0 35 85 2.16 2.31E-43
204897 at PTGER4 1.62 0 37 671 3.53 0.000000015
211548 s at HPGD 1.60 0 38 185 Inline graphicDIV0! 3.19E-25
220014 at PRR16 1.50 0 44 NA NA NA
219476 at C1orf116 1.47 0 46 96 1.94 5.44E-39
203180 at ALDH1A3 1.46 0 48 668 1.29 1.44E-08
210787 s at CAMKK2 1.42 0 49 NA NA NA
201110 s at THBS1 1.38 0 51 NA NA NA

The list of identifiers and their associated genes extracted from the microarray using SamR analysis and put to the sscMap. 18 out these 23 gene identifiers are also identified as differentially expressed genes (DEGs) by the DESeq analysis on the NGS dataset (Table S1). NA indicates that the corresponding gene was not returned as DEG by DESeq and hence is not found in Table S1. Expression fold change is defined as ratio (stimulated/unstimulated). Inline graphic Note that Dseq reported 0 expression for this gene in the unstimulated state, hence ratio(stimulated/unstimulated) and logratio are not defined. Table S5 also contains the signed ranks of these 23 probesetIDs in the 6 instances of reference profiles for cotinine.