Skip to main content
. 2013 Jun 26;8(6):e66902. doi: 10.1371/journal.pone.0066902

Table 5. Compounds declared significant between both technologies that had full perturbation stability.

refsetname setsize queryName queryLength setscore sig Per refsetname setsize queryName queryLength setscore sig Per
cotinine 6 RNA-seq 10 −0.598 1 1 cotinine 6 Microarray 23 −0.377 1 1
morantel 5 RNA-seq 10 −0.557 1 1 morantel 5 Microarray 23 −0.366 1 1
tobramycin 4 RNA-seq 10 −0.671 1 1 chlorphenesin 4 Microarray 23 −0.398 1 1
trioxysalen 4 RNA-seq 10 −0.658 1 1 trioxysalen 4 Microarray 23 −0.383 1 1
pentoxyverine 4 RNA-seq 10 −0.601 1 1 trimetazidine 4 Microarray 23 −0.370 1 1
levamisole 4 RNA-seq 10 −0.569 1 1 pentoxyverine 4 Microarray 23 −0.369 1 1
trimetazidine 4 RNA-seq 10 −0.552 1 1 levamisole 4 Microarray 23 −0.356 1 1
chlorphenesin 4 RNA-seq 10 −0.548 1 1 lysergol 4 Microarray 23 −0.349 1 1
oxprenolol 4 RNA-seq 10 −0.535 1 1 tobramycin 4 Microarray 23 −0.348 1 1
zomepirac 4 RNA-seq 10 −0.533 1 1 oxprenolol 4 Microarray 23 −0.336 1 1
lysergol 4 RNA-seq 10 −0.505 1 1 zomepirac 4 Microarray 23 −0.330 1 1
fosfosal 4 RNA-seq 10 −0.428 1 1 fosfosal 4 Microarray 23 −0.280 1 1
sertaconazole 4 RNA-seq 10 −0.411 1 1 sertaconazole 4 Microarray 23 −0.256 1 1
abamectin 4 RNA-seq 10 −0.392 1 1 abamectin 4 Microarray 23 −0.245 1 1
saquinavir 4 RNA-seq 10 −0.359 1 1 saquinavir 4 Microarray 23 −0.243 1 1
ipratropium bromide 3 RNA-seq 10 −0.564 1 1 ipratropium bromide 3 Microarray 23 −0.365 1 1
furazolidone 4 RNA-seq 10 0.602 1 1 furazolidone 4 Microarray 23 0.344 1 1
5186223 1 RNA-seq 10 0.701 1 1 5186223 1 Microarray 23 0.504 1 1

The list of compounds that overlapped between the two technologies, which was 18 out of a possible 64. 16 of the 18 compounds were candidates that would potentially suppress the phenotype. queryLength is the number of genes included in the query gene signature. refset is the set of reference profiles for a compound in the cmap database; Setsize is the size of the set of Reference Profiles for that compound in the cmap core database. sig = 1 indicates the connection score is statistically significant; Per = 1 means that the connection has full perturbation stability.