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. Author manuscript; available in PMC: 2013 Jun 26.
Published in final edited form as: Otolaryngol Head Neck Surg. 2012 Jul 11;147(5):975–977. doi: 10.1177/0194599812454271

Table 1.

Patients in This Study: Type of Hearing Loss, Inheritance, Genes Screened, Audiogene Prediction, and Final Result

Patient Inheritance Type of Hearing Loss OtoSCOPE Result: Genes with VUS AudioGene Prediction Final Result
Patient 1 Dominant Up-sloping DSPP, LRTOMT, WFS1 DFNA6 (WFS1), DFNA11 (MYO7A), DFNA8/12 (TECTA) WFS1 p.R685P
Patient 2 Dominant Down-sloping CDH23, GPR98, KCNQ4, WFS1 DFNA2 (KCNQ4), DFNA10 (EYA4), DFNA9 (COCH) KNCQ4 p.L281S
Patient 3 Dominant Sharply down-sloping MYO1A, MYO7A, OTOA, PCDH15, TRIOBP (2) DFNA2 (KCNQ4), DFNA9 (COCH), DFNA25 (SLC17A8) MYO7A p.R1743W

Abbreviation: VUS, variants of unknown significance.