Table 1.

Gastric Protection Against Ethanol-Induced Mucosal Lesions by Central Injection of TRH Analog, RX-77368, FYY and CGRP-Related Peptides

Peptides	Dose (pmol/rat)	Route	Gastric Ethanol %	Gastric Protection %	References
RX-77368	7–26	DMN	60%	79–61%	[49]
RX-77368	3.8	ic	60%	78–88%	[46,47]
RX-77368	2.5–3.8	ic	60%	58–78%	[45]
RX-77368	1.5	DVC	60%	57%	[51]
RX-77368	25–38	ic	60%	43–77%	[50]
RX-77368	4	ic	45%	59%	[18]
TRH	19	ic	60%	63%	[48]
PYY	23–117	ic	45%	27–63%	[18,92]
PYY+RX-77368	6+2	ic	45%	44%	[18]
[Pro34]PYY	12–120	ic	45%	30–75%	[59]
[Pro34]PYY+RX-77368	6+2	ic+ic	45%	43%	[59]
α-CGRP	8–80	ic	40%	76–97%	[22]
α-CGRP	150	ic	70%	76%	[24]
Adrenomedullin	75–150	ic	70%	42–70%	[24]
Amylin	169–560	icv	50%	50–60%	[105,121]
Calcitonin	28	ic	40%	0%	[23]
Calcitonin	28–550	icv	50%	0%	[105]

DMN: dorsal motor nucleus of the vagus; DVC: dorsal vagal complex; ic: intracisternal; icv: intracerebroventricular.