Table 2. Cox proportional regression analysis for the prediction of the PCa patients' DFS.

	Univariate analysis			Multivariate analysis
Covariant	HR	95% CIa	P-valueb	HR	95% CIa	P-valueb
miR-145
Positive	1.00			1.00
Negative	2.533	1.249–5.137	0.010	1.264	0.489–3.273	0.629
Gleason score	2.244	1.407–3.578	0.001	1.660	0.944–2.921	0.078
Clinical stage	1.504	1.178–1.922	0.001	1.151	0.818–1.621	0.419
PSA	1.092	1.035–1.151	0.001	1.034	0.957–1.117	0.397
Age	0.996	0.944–1.051	0.877	0.983	0.930–1.039	0.548
DRE	2.285	1.104–4.727	0.026	1.535	0.679–3.469	0.303

Abbreviations: CI=confidence interval; DFS=disease-free survival; DRE=digital rectal examination; HR=hazard ratio; PCa=prostate cancer.

^aCI of the estimated HR.

^bTest for trend.