Table 1. Characteristics of the 98 colorectal neoplastic lesions assessed for NGAL expression.
| Characteristics | CaP identified from diagnostic database (n=52) | Adenomas collected within paired polyp–normal sample set (n=46) |
|---|---|---|
| Colonic site |
50 (96%) distal to splenic flexure |
38 (83%) distal to splenic flexure |
| Size |
1(2%) small <1cm, 51 (98%) large >1 cm |
16 (35%) small <1 cm, 30 (65%) large ⩾1 cm |
| Size range |
0.8–3.1 cm |
0.3–3 cm |
| Histological classification of adenomatous epithelium |
31 (%) tubular adenoma, 21 (%) tubulo-villous adenomaa |
41 (89%) tubular adenoma, 5 (11%) tubulo-villous adenoma |
| Degree of dysplasia of adenomatous epithelium | 4 (7%) LGD, 12 (27%) LGD/HGD, 31 (66%) HGDa | All LGD |
Abbreviations: HGD=high-grade dysplasia; LGD=low-grade dysplasia; LGD/HGD=LGD background with foci of HGD.
a
n=47; four CaP lesions had no adenomatous epithelium seen on stained section and therefore excluded.