Table 3. Localisation of NGAL positivity (epithelial/stromal) in each histological compartment of CaP lesions.
Normal colonic mucosa n=47(*,**) | Adenoma n=47(*,***) | Carcinoma n=33(**,***) | |
---|---|---|---|
Epithelial cell NGAL positivea |
0 (0%) |
43 (92%) |
19 (58%) |
Epithelial cell NGAL negativea |
47 (100%) |
4 (8%) |
14 (42%) |
Stromal cell positiveb |
2 (4%) |
46 (98%) |
33 (100%) |
Stomal cell negativeb | 45 (96%) | 1 (2%) | 0 (0%) |
Abbreviations: CaP=cancer polyp; NGAL=neutrophil gelatinase-associated lipocalin.
Normal vs Adenoma, χ=75.6, P=0.0001.
Normal vs Carcinoma, χ=32.4, P=0.0001.
Adenoma vs Carcinoma, χ=10.9, P=0.001.
Normal vs Adenoma, χ=78.7, P=0.0001.
Normal vs Carcinoma, χ=68.4, P=0.0001.
Adenoma vs Carcinoma, not significant.