Figure 2.
Neuronal projections in the hippocampus. Schematic representation of the coronal view of the hippocampus region indicating the subregions of the hippocampus and their location within the hippocampus. CA, cornu ammonis; Trisynaptic circuitry in the hippocampus is indicated with axons from the entorhinal cortex projecting unidirectionally to the apical dendrites of the hippocampal DG, CA1, and CA3 neurons (perforant path projection). DG neurons project to the apical dendrites of the CA3 pyramidal neurons (mossy fiber projection). CA3 neurons project to the apical dendrites of the CA1 neurons (Schaffer collateral projection). The CA1 neurons have bidirectional projections to and from the BLA. The BLA also sends projections to the medial prefrontal cortex (mPFC), nucleus accumbens (NAc), bed nucleus of the stria terminalis (BNST), and central nucleus of the amygdala.