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Laser-capture microdissection of CHOP in F4/80+ phagocytes of atherosclerotic plaque. (A) Aortic root lesions from LDLR–/– mice were stained with F4/80 and (B) a parallel section captured by LCM. Sections were cut at 6-μm thickness. (C) An image of the lesion after capture is shown. (D) CHOP qRT-PCR of targeted F4/80+ areas reveals increased CHOP expression after increased diet duration. ★p < 0.05.
