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. Author manuscript; available in PMC: 2013 Jun 27.
Published in final edited form as: J Heart Valve Dis. 2012 Mar;21(2):234–240.

Figure 4.

Figure 4

Similar pathways in valve development and disease. Mechanisms such as vascularization, ECM organization, and cell migration are controlled by common molecules including, but not limited to, TGF-β, VEGF, chondromodulin-1, and tenascin-C.