The Effects of Repressing Ribosome Synthesis on Protein Production during Amino Acid Starvation, Related to Figure 7
During starvation, cells usually respond by repressing ribosome production. Reducing ribosomes under normal or mild-stress conditions always reduces protein production. However, for many amino acids (e.g., A, E, L, P, Q, S, V), reducing ribosomes by small amounts partly rescues protein production under amino-acid starvation. The y axis shows the total rate of protein production relative to a wild-type cell without any amino-acid starvation.