Table 6.
Univariate and Multivariate Generalized Linear Latent and Mixed Model Logistic Regression Models for Central Corneal Opacity⁎
| Variable | Pupil Obscuring/Central Corneal Opacity |
||
|---|---|---|---|
| OR§ | 95% CI | P Value | |
| Univariate analysis | |||
| Gender | |||
| Male | 1 | — | — |
| Female | 0.81 | 0.61–1.08 | 0.154 |
| Advancing age† | 1.52 | 1.39–1.67 | <0.005 |
| Epilation status | |||
| No epilation | 1 | — | — |
| Unsuccessful epilation | 1.18 | 0.92–1.52 | 0.200 |
| Successful epilation | 0.57 | 0.40–0.81 | 0.002 |
| Entropion grade‡ | |||
| 0 | 1 | — | — |
| 1 | 1.54 | 1.12–2.12 | 0.008 |
| 2 | 3.55 | 2.54–4.96 | <0.005 |
| 3 | 8.36 | 5.34–13.09 | <0.005 |
| 4 | 44.98 | 26.20–77.20 | <0.005 |
| Multivariate logistic regression model | |||
| Advancing age | 1.63 | 1.48–1.80 | <0.005 |
| Unsuccessful epilation | 0.87 | 0.66–1.13 | 0.29 |
| Successful epilation | 0.61 | 0.43–0.88 | 0.007 |
| Entropion grade‡ | |||
| 0 | 1 | — | — |
| 1 | 1.68 | 1.22–2.31 | 0.002 |
| 2 | 4.15 | 2.93–5.86 | <0.005 |
| 3 | 9.49 | 6.05–14.86 | <0.005 |
| 4 | 45.07 | 26.29–77.26 | <0.005 |
CI = confidence interval; OR = odds ratio.
⁎
For the generalized linear latent and mixed model outcome, corneal opacity subdivided into 4 groups: (1) CO 0/1 (no or peripheral opacity), (2) CO 2a/2b (central 4 mm, not overlying visual axis), (3) CO 2c/2d (overlying visual axis, but not obscuring all central 4 mm), and (4) CO 3 (overlying whole central 4 mm). Phthisis (CO 4) excluded.
†
Advancing age group has a linear association with increasing corneal opacity.
‡
Entropion grades 1–4 are compared with entropion grade 0.