Fig. 2.

Gene expression of phenotype markers over time in response to M1 or M2 inducing conditions. Expression of phenotype markers grouped as M1 (White), M2a (grey) or M2b (black) dependent on their proposed function, in primary microglia exposed to M1/2b inducing conditions (+LPS) or M2a inducing conditions (+IL-4), for 4 h, 12 h, 36 h or 72 h. Expression shown relative to PBS only, dotted line. Data are mean ± SEM of at least 3 experiments. Data were assessed via an ANOVA, and where significant the results of the Bonferroni post-test are shown; ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001, compared to PBS.