. Author manuscript; available in PMC: 2013 Jun 27.

Published in final edited form as: Trends Neurosci. 2003 Nov;26(11):610–617. doi: 10.1016/j.tins.2003.09.008

Table 1.

Comparison of main and substate conductances of cell–cell channels and hemichannels (pS)^a

Connexin	Cell–cell: open	Substate observed (calculated)	Refs	Hemichannel: open	Substate observed (calculated)	Refs
Cx30	146	25 (41)	[43]	283	48 (30)	[44]
Cx43	115	30 (56)	[4]	220	75 (40)	[22]
Cx45	30	4 (12)	[47]	62	15 (4.6)	[46]
Cx46	150	28 (75)	[45]	300	100 (33)	[45]
		(32)		250	37 (34)	[44]
Cx50	203	33 (60)	[44]	357	77 (39)	[44]

Substate conductances usually do not follow from simple series arrangement of hemichannels in cell–cell channels (Figure 1) (access resistance is neglected).