3H-cAMP accumulation in response to cimaterol in (a)
CHO β1 cells, (b) CHO β2 cells,
and (c) CHO β3 cells in the absence and presence
of 19. Bars show basal 3H-cAMP accumulation,
that in response to 10 μM isoprenaline, and that in response
to 30 nM, 100 nM, 300 nM, 1 μM, 3 μM, and 10 μM 19 alone. Data points are the mean ± SEM of triplicate
values from single experiments that are representative of seven separate
experiments in each case.