Figure 2. Effect of MSC transplantation on functional outcome.
Rats underwent MCAO at p10 and were treated with vehicle or MSC at 3 days post-MCAo. Lateralizing motor deficits were measured in the cylinder rearing test at 14, 21 and 28 days post-MCAo (A) and using the adhesive removal test at 28 days post-MCAo (B). Data represent mean±SEM. Sham-controls n=5, VEH n=8, MSC n=9, MSC-BDNF n=8. *p<0.05 vs. VEH, #p<0.05 MSC-BDNF vs. MSC.