Table 3.
Ovarian response to stimulation and outcome of IVF treatment according to LH genotype
| Group Awild-type LH n = 196 | Group Bv-betaLH n = 24 | p value A vs B | |
|---|---|---|---|
|
Estradiol Day S1 (nmol/L) |
0.1 ± 0.1 |
0.1 ± 0.1 |
NS |
|
Estradiol Day S8 (nmol/L) |
3.9 ± 2.8 |
3.4 ± 3.0 |
NS |
|
Androstenedione on Day of trigger (ng/mL) |
1.5 ± 0.8 |
2.1 ± 1.3 |
0.012 |
|
Androstenedione on OPU (ng/mL) |
5.35 ± 2.4 |
5.53 ± 2.3 |
NS |
|
LH (IU/L) Day S1 |
1.9 ± 0.9 |
2.1 ± 1.3 |
NS |
|
LH (IU/L) Day S8 |
1.9 ± 1.25 |
1.8 ± 0.95 |
NS |
|
LH (IU/L) Day OPU |
0.1 ± 0.1 |
0.1 ± 0.7 |
NS |
|
Cumulative FSH dose (IU) |
1959.8 ± 736.45 |
2435.9 ± 932.8 |
0.048 |
|
N. mature oocytes retrieved* |
8.6 ± 4.9 |
7.3 ± 4.85 |
NS |
|
N. embryos transferred* |
1.6 ± 0.8 |
1.3 ± 0.6 |
0.042 |
|
Fertilization rate (%) |
52 |
46 |
NS |
| Positive betahCG (%) | 37 | 45 | NS |
Values are expressed as mean ± SD.
Abbreviations: NS not statistically significant; oPu ovum pick up.