Table 3.
Adjusted hazard ratios of overall, 4-year mortality associated with study period (for all 214 patients over 75 years)
| |
Model-1 |
Mdel-2 |
Model-3 |
Model-4 |
Model-5 |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Demographics |
Demographics + Comorbidity |
Demographics + Mobility |
Demographics + Care |
1 + 2 + 3 + 4 |
|||||||||||
| HR | 95% CI | p | HR | 95% CI | p | HR | 95% CI | p | HR | 95% CI | p | HR | 95% CI | p | |
|
Dialysis initiation year. reference: |
2002-2004 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 2005-2007 |
0.81 |
0.69-0.95 |
0.010* |
0.85 |
0.72-0,999 |
0.049* |
0.88 |
0.74-1.06 |
NS |
0.85 |
0.72-1.00 |
0.052 |
0.94 |
0.78-1.13 |
NS |
|
Age. reference: 75–84 years |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| ≥85 years |
1.22 |
0.99-1.48 |
0.06 |
1.27 |
1.03-1.54 |
0.027* |
1.18 |
0.95-1.44 |
NS |
1.20 |
0.97-1.46 |
0.09 |
1.21 |
0.97-1.48 |
0.09 |
|
Gender. reference: Male |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Female |
0.99 |
0.84-1.17 |
NS |
1.00 |
0.84-1.18 |
NS |
0.95 |
0.80-1.13 |
NS |
0.97 |
0.81-1.15 |
NS |
0.96 |
0.80-1.15 |
NS |
|
Comobidities. reference: without this comorbidity |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Heart failure |
|
|
|
1.31 |
1.11-1.55 |
0.001* |
|
|
|
|
|
|
1.23 |
1.04-1.46 |
0.018* |
| Diabetes |
|
|
|
1.21 |
1.02-1.43 |
0.030* |
|
|
|
|
|
|
1.12 |
0.94-1.93 |
0.10 |
|
Mobility. reference: walk out help |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Need assistance for transfers |
|
|
|
|
|
|
1.43 |
1.16-1.74 |
<0.001* |
|
|
|
1.40 |
1.13-1.71 |
0.002* |
| Tatally dependent for transfers |
|
|
|
|
|
|
1.42 |
0.97-1.96 |
0.07 |
|
|
|
1.38 |
0.94-1.93 |
0.10 |
|
Dailysis modality. reference: HD with fistula |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| HD without fistula |
|
|
|
|
|
|
|
|
|
1.29 |
1.03-1.62 |
0.025* |
1.16 |
0.92-1.48 |
NS |
| PD |
|
|
|
|
|
|
|
|
|
1.49 |
1.19-1.89 |
<0.001* |
1.38 |
1.09-1.76 |
0.008* |
|
Baseline eGFR. reference: 7 ≥ eGFR < 10 ml/min/1.73 m2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| eGFR < 7 ml/min/1.73 m2 |
|
|
|
|
|
|
|
|
|
1.08 |
0.88-1.33 |
NS |
1.18 |
0.95-1.46 |
NS |
| eGFR ≥ 10 ml/min/1.73 m2 |
|
|
|
|
|
|
|
|
|
1.25 |
1.00-1.56 |
0.047* |
1.36 |
1.08-1.71 |
0.009 |
| Missing | 1.13 | 0.79-1.55 | NS | 1.12 | 0.77-1.57 | NS | |||||||||
HD hemodialysis, PD peritoneal dialysis, eGFR estimated glomerular filtration rate, HR hazard ratio, 95% CI 95% confidence intervals.
Model-1 was adjusted for age and gender.
Model-2 was adjusted as Model-1 + heart failure and diabetes.
Model-3 was adjusted as Model-1 + mobility.
Model-4 was adjusted as Model-1 + dialysis modality and baseline eGFR.
Model-5 was adjusted for all variables in previous models.
NS Not Significant (with p > 0.1).