TABLE II.
Results of Univariate Analyses for Lifetime Rates of DSM-IV Obsessive-Compulsive Disorder (OCD) and MOCI Scores Using Random Effects Model Within Generalized Least Squares Regression
| (A) Score and percents of each MOCI scale in manifesting carriers, non-manifesting carriers, and non-carriers
| ||||
|---|---|---|---|---|
| Diagnosis | MOCI score* | Manifesting carriers (n = 96)
|
Non-Manifesting carriers (n = 60)
|
Non-carriers (n =65)
|
| No. (%) | # No. (%) | No. (%) | ||
| OCD | 3 (3.13) | 1 (1.70) | 3 (4.60) | |
|
| ||||
| MOCI-total | Score ≥ 3 | 48 (50.0) | 34 (56.7) | 32 (49.2) |
| Score M < 3 | 48 (50.0) | 26 (43.3) | 33 (50.8) | |
| MOCI-check | Score = 0 | 50 (52.1) | 37 (61.7) | 34 (52.3) |
| Score > 0 | 46 (47.9) | 23 (38.3) | 31 (47.7) | |
| MOCI-wash | Score = 0 | 42 (43.8) | 28 (46.7) | 27 (41.5) |
| Score > 0 | 54 (56.3) | 32 (53.3) | 38 (58.5) | |
| MOCI-slow | Score ≤ 2 | 58 (60.4) | 44 (73.3) | 40 (61.5) |
| Score > 2 | 38 (39.6) | 16 (26.7) | 25 (38.5) | |
| MOCI-doubt | Score ≤ 1 | 40 (41.7) | 25 (41.7) | 25 (38.5) |
| Score > 1 | 56 (58.3) | 35 (58.3) | 40 (61.5) | |
|
| ||||
| (B) Results of univariate analyses for MOCI scores
| ||||
| All carriers vs. non-carriers
|
Non-manifesting carriers vs non-carriers
|
Manifesting carriers vs non-carriers
|
Manifesting vs non-manifesting carriers
|
|
| Diagnosis | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) |
|
| ||||
| MOCI-total | 0.67 (0.21–2.16) | 0.41 (0.10–1.59) | 0.92 (0.25–3.48) | 2.27 (0.63–8.11) |
| MOCI-check | 0.97 (0.65–1.44) | 0.81 (0.51–1.29) | 1.06 (0.67–1.65) | 1.33 (0.86–2.07) |
| MOCI-wash | 0.88 (0.54–1.41) | 0.75 (0.44–1.29) | 0.97 (0.57–1.66) | 1.29 (0.75–2.22) |
| MOCI-slow | 1.02 (0.80–1.31) | 0.84 (0.65–1.09) | 1.16 (0.87–1.54) | 1.38 (1.06–1.81)a |
| MOCI-doubt | 0.87 (0.57–1.35) | 0.82 (0.49–1.37) | 0.91 (0.56–1.46) | 1.10 (0.68–1.80) |
*
MOCI scores categorized as bivariate for table clarity but are included as continuous in analyses
a
Significantly different (P < 0.05).