Figure 4.

While there was no significant relationship between the percentage of monocytes expressing anthrax toxin receptor 1 (ANTXR1) and interferon (IFN)-γ enzyme-linked immunospot (ELISPOT) responses to protective antigen (PA) in anthrax vaccine precipitated (AVP)-vaccinated subjects (a) and naturally infected individuals showed an inverse correlation between ANTRXR1 expression and IFN-γ responses to PA (b), i.e. those individuals with the lowest percentage of ANTXR1-positive monocytes showed the highest levels of IFN-γ production in response to PA stimulation.