. Author manuscript; available in PMC: 2013 Jun 27.

Published in final edited form as: Neuropsychopharmacology. 2009 Jun 24;34(11):2459–2468. doi: 10.1038/npp.2009.68

Table 1.

Regulation of VEGF in the Hippocampus by 5-HT1A Receptor Selective Agents

Treatment	VEGF protein levels pg/mg
Experiment 1
Saline	10.3 ± 0.3
8–OH-DPAT	12.2 ± 0.7^*
Experiment 2
Saline	10.2 ± 0.6
WAY100635	8.6 ± 0.4^*
Experiment 3
Saline + saline	12.9 ± 0.2
Saline+8–OH-DPAT	15.0 ± 0.8^*
WAY100635+8-OH-DPAT	12.8 ± 0.5^#

8-OH-DPAT and WAY100635 were administrated as described in ‘Materials and Methods’ and levels of hippocampal VEGF were determined by ELISA. Results are expressed as mean±SEM pg VEGF/mg total protein.

P<0.05 compared with saline treated animals

P<0.05 compared to 8-OH-DPAT treated animals (ANOVA and Fisher’s post hoc test).