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. Author manuscript; available in PMC: 2013 Jun 27.
Published in final edited form as: Cardiol Clin. 2011 Aug;29(3):461–477. doi: 10.1016/j.ccl.2011.06.002

Fig. 13.

Fig. 13

Plots of peak systolic blood pressure (BP) and exercise duration during baseline, during placebo administration, and during losartan administration in a randomized, controlled, cross-over trial. Treatment with the angiotensin II antagonist losartan increased exercise time. (From Warner JG, Metzger C, Kitzman DW, et al. Losartan improves exercise tolerance in patients with diastolic dysfunction and a hypertensive response to exercise. J Am Coll Cardiol 1999;33:1567-72; with permission. Copyright © 1999, American College of Cardiology.)