Table 2. ABCC1 Cotransports [3H]GSH and M3G.
Microsomes isolated from yeast cells expressing ABCC1 transport GSH only in the presence of M3G. Empty vector–transformed yeast cells were used as a negative control. Transport assays were performed at room temperature for 15 min. To exclude the endogenous proton gradient-driven GSH transport, NH4Cl was added to the transport mix. The data represent the mean of three independent uptake experiments ± se; nd, not detectable. Asterisk indicates statistical significance (Student’s t test; P < 0.05).