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. 2013 Apr 24;33(17):7439–7450. doi: 10.1523/JNEUROSCI.4506-12.2013

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Figure 11. — Astrocyte changes are widespread in the neocortex of GFAP^Tg;Gfap^+/R236H mice. Note the difference between levels of GFAP in neocortex in 2 and 4 week GFAP^Tg;Gfap^+/R236H (A and B, respectively) mice versus age-matched WT mice (C and D, respectively). E, F, Reactive astrocytes populate the piriform cortex in GFAP^Tg;Gfap^+/R236H mouse (E) and are absent from piriform cortex in WT mouse (F). Astrocytes around blood vessels (arrows, B, E) stained strongly for GFAP. Confocal microscopy; scale bars: A–D, 350 μm; E, F, 200 μm.