Figure 11. PYR1 main chain flexibility profiles in ABA-free PYR1 dimer (red line), 2ABA-bound PYR1 dimer (green line), and ABA-bound PYR1 in complex with HAB1 (blue line).

Overall, the main chain of PYR1 is more flexible in the dimers than in the PYR1-HAB1 complex. Dashed lines indicate the regions of dimer binding. The level of PYR1 flexibility in the dimer/HAB1 complex is essentially reduced comparing to that of PYR1 monomer (Figure 3).