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. 2013 Jun 27;7(6):e2289. doi: 10.1371/journal.pntd.0002289

Table 3. Comparison of four rapid diagnostic tests on randomly-selected serum samples.

MAT Pasteur RDT 1/400 Leptocheck Elisa Serion (+RF absorbant) Elisa Panbio
Positive 72 Positive 59 Positive 59 Positive 58 Positive 53
Negative 5
Negative 1 Positive 0
Negative 1
Negative 0 Positive 0 Positive 0
Negative 0
Negative 0 Positive 0
Negative 0
Negative 13 Positive 11 Positive 8 Positive 1
Negative 7
Negative 3 Positive 0
Negative 3
Negative 2 Positive 0 Positive 0
Negative 0
Negative 2 Positive 0
Negative 2
Sensitivity 81.9% [71.5–89.1] 97.2% [90.4–99.2] 91.7% [83–86.1] 75% [63.9–83.6]
Negative 72 Negative 69 Negative 38 Negative 59 Negative 72
Specificity 95.8% [88.4–98.6] 52.8% [41.4–63.9] 81.9% [71.5–89.1] 100% [94.9–100]
LR+ * 19.7 [6.5–59.9] 2.1 [1.6–2.6] 5.1 [3.1–8.3] NA
LR− 0.2 [0.1–0.3] 0.05 [0.01–0.21] 0.1 [0.05–0.2] 0.25 [0.17–0.37]
DOR 104.4 [28.4–384] 39.1 [8.9–171.8] 49.9 [17.8–139.7] NA

NA: Not Applicable.

*

LR+: Positive Likelihood Ratio – [95% CI].

LR−: Negative Likelihood Ratio – [95% CI].

DOR: Diagnostic Odds Ratio – [95% CI].

Sensitivity (%), number of positive rapid diagnostic test among patients with serological evidence (MAT) of leptospirosis (n = 72) – [95% CI].

Specificity (%), negative rapid diagnostic test among serum samples from patients with no serological evidence (MAT) of leptospirosis (n = 72) – [95% CI].