Table 1. Sequencing reads covering rRNAs and tRNAs in the studied organisms.

Organism	# reads mapped to rRNA	# reads mapped to tRNA	% cytosines converted to uracilsa	# rRNA	# rRNA genes with mean coverage >5	# tRNA	# tRNA genes with mean coverage >5	% tRNAs covered
B. subtilis	4,786,857	42,425	98.3%	2	2	43	32	74%
E. coli	206,162	168,557	98.7%	2	2	49	47	96%
S. solfataricus	12,654,256	5,626	97.6%	2	2	44	39	89%
S. cerevisiae	1,215,559	18,782	98.4%	4	4	51	35	69%

^aConversion rates were calculated out of the raw data prior to filtering.