Table 2. Differentially regulated genes between SIV+ CD4-low and SIV+ CD4-healthy mangabeys.

Fold change – Higher in CD4-low				Fold change – Higher in CD4-Healthy
Gene	CD4 Healthy	CD4 Low	Ratio L/H	Gene	CD4 Healthy	CD4 Low	Ratio H/L
Upregulated genes				Upregulated genes
RGS4	4.0	19.6	4.8	TWIST1	9.5	4.3	2.2
TAF4B	5.6	18.7	3.3	DDX21	6.9	4.3	1.6
CPXM1	5.7	17.8	3.1	IL2RA	7.6	4.7	1.6
TSLP	4.7	12.5	2.7	IL22	42	28.5	1.5
NETO2	5.3	13.4	2.5	Downregulated genes
FRMD4B	5.9	14.9	2.5	ARHGAP6	7.2	4.1	1.8
SLC16A1	4.4	10.0	2.3	ANKRD58	13.6	8.7	1.6
TNIP3	13.2	28.0	2.1	KLHL3	8.9	6.0	1.5
IL12B	4.4	8.0	1.8
ZBED2	17.2	31.7	1.8
GBP1	4.6	8.3	1.8
IL21	13.0	21.7	1.7
SLC26A4	5.0	8.3	1.7
RIPK2	9.0	14.7	1.6
PRRX2	7.5	12.2	1.6
CXCL10	8.1	13.0	1.6
Downregulated genes
SMAD7	4.2	9.5	2.3
PSRC1	7.6	15.0	2.0
NOG	14.9	28.7	1.9
PIK3IP1	4.7	8.6	1.8
ERP27	4.6	8.2	1.8
SNPH	6.4	11.3	1.8
ROM1	5.0	8.5	1.7
ARAP3	4.9	8.1	1.6
CSPG5	8.1	13.0	1.6
FRMD3	4.4	7.0	1.6