Table 1. Baseline characteristics of the study cohort.
Parameter | |
Gender (n) | |
-Male | 20 (61%) |
-Female | 13 (39%) |
Age (years) | |
-Mean ± SD | 44±14 |
HBeAg status (n) | |
-HBeAg positive | 12 (36%) |
-HBeAg negative | 15 (45%) |
Inactive HBsAg carrier (n) | 6 (18%) |
Ethnicity | |
-Caucasian | 27 (82%) |
-Asian | 4 (12%) |
-Afro-American | 2 (6%) |
Genotype (n) | |
-Genotype A | 18 (54%) |
-Genotype B | 1 (3%) |
-Genotype C | 3 (9%) |
-Genotype D | 10 (30%) |
-Genotype E | 1 (3%) |
Hepatic Fibrosis (Ishak staging) (n) | |
F0 | 3 (9%) |
F1 | 6 (18%) |
F2 | 6 (18%) |
F3 | 2 (6%) |
F4 | 1 (3%) |
F5 | 2 (6%) |
F6 | 0 |
Not available | 13 (39%) |
Organ transplantation (n) | |
-Liver transplantation | 5 (15%) |
-Renal transplantation | 4 (12%) |
Duration of NUC therapy (months) | |
-Mean ± SD | 34±21 |
-Median (range) | 28 (11–111) |
Treatment regimen (n) | |
-Lamivudine (LAM) monotherapy | 8 |
-Adefovir (ADV) monotherapy | 6 |
-Telbivudine (LDT) monotherapy | 1 |
-Entecavir (ETV) monotherapy | 2 |
-Tenofovir (TDF) monotherapy | 2 |
-Lamivudine+Adefovir | 6 |
-Lamivudine/Entricitabine+Tenofovir | 6 |
-Tenofovir+Entecavir | 5 |