Table 2. Lung functional and analytical characteristics.
| Variables | All patients (n=71) | Non LVDD (n=7) | LVDD (n=64) |
|---|---|---|---|
| FVC, % pred | 73.1 ± 14.9 | 85.9 ± 7.5 | 74.9 ± 15.1 |
| FEV1, % pred | 38.5 ± 6.1 | 36.9 ± 4.4 | 38.7 ± 6.3 |
| TLC, % pred | 127.4 ± 23.2 | 128.7 ± 15.2 | 127.2 ± 24.1 |
| RV, % pred | 216.4 ± 76.8 | 210.4 ± 38.7 | 217.1 ± 80.5 |
| IC/TLC ratio | 0.27 ± 0.07 | 0.30 ± 0.04 | 0.27 ± 0.07 |
| DLCO/VA, % pred | 63.2 ± 21.9 | 56.1 ± 27.2 | 64.1 ± 21.3 |
| mMRC scale I–II/III, n (%) | 54 (76) / 17 (24) | 6 (85.7) / 1 (14.3) | 48 (75) / 16 (25) |
| 6MWD, m | 372.1 ± 86.4 | 413.9 ± 43.2 | 367.5 ± 88.9 |
| CRP, mg/L | 8.3 ± 9.4 | 1.5 ± 0.8 | 8.9 ± 9.6* |
| NT-proBNP, ng/L | 79.3 ± 70.4 | 64.3 ± 35.7 | 80.8 ± 72.9 |
| PaO2, mmHg | 68.4 ± 9.4 | 71.6 ± 12.3 | 68.1 ± 9.0 |
| PaCO2, mmHg | 44.1 ± 5.5 | 44.4 ± 5.8 | 43.9 ± 5.5 |
Definition of abbreviations: LVDD = left ventricle diastolic dysfunction; FVC = forced vital capacity; % pred = % predicted; FEV1 = forced expiratory volume in 1 second; TLC = total lung capacity; RV = residual volume; IC/TLC = inspiratory-to-total lung capacity ratio; DLCO/VA = lung diffusion capacity corrected for alveolar ventilation; mMRC = modified Medical Research Council dyspnea scale; 6MWD = 6-minute walking distance; CRP = C-reactive protein; NT-proBNP = N-terminal pro-B-type natriuretic peptide. Values are expressed as mean±standard deviation or frequencies and percentages. *p < 0,05.