Table 3. Nuclear SOX4 expression in colon cancer and its association with clinicopathologic parameters.

		Nuclear SOX4 expression
		Score = 0 or 1	Score = 2 or 3
		(n = 144)	(n = 119)
Variable	n	<1.54	≥1.54	P *
Age (yr)				0.2313
≥68	162	84	78
<68	101	60	41
Gender				0.2774
Male	154	80	74
Female	109	64	45
Depth of invasion				0.0041
T1	11	9	2
T2	22	16	6
T3	198	109	89
T4	32	10	22
Nodal status				0.3198
N0	126	73	53
N1+ N2+ N3	137	71	66
Distant metastasis				<0.0001
Absent	224	134	90
Present	39	10	29
Stage				0.0001
I	25	20	5
II	91	51	40
III	108	63	45
IV	39	10	29
Degree of differentiation				0.0513
Poor	16	5	11
Well to moderate	247	139	108
Vascular invasion				0.2050
Absent	124	73	51
Present	139	71	68
Perineural invasion				0.7162
Absent	206	114	92
Present	57	30	27

^*All statistical tests were two-tailed and the significance level was P<0.05.