Table 2. Factors associated with primary HIV drug resistance by duration of HIV infection - univariate logistic regression.
Variables | Recent HIV infection | Chronic HIV infection | ||||
Odds ratio | 95% Confidence interval | p-value* | Odds ratio | 95% Confidence interval | p-value* | |
Age groups, years | 0.054 | 0.112 | ||||
≤30 | 1 | 1 | ||||
31–40 | 3.64 | 1.44–9.20 | 0.006 | 0.63 | 0.33–1.21 | 0.168 |
41–50 | 1.41 | 0.18–11.29 | 0.746 | 0.55 | 0.25–1.18 | 0.125 |
≥51 | 6.58 | 0.65–66.25 | 0.110 | 0.44 | 0.15–1.34 | 0.151 |
Gender | ||||||
Female | 1 | 1 | ||||
Male | 2.47 | 0.32–18.69 | 0.382 | 1.24 | 0.68–2.25 | 0.480 |
Ethnicity | ||||||
Non Thai | 1 | 1 | ||||
Thai | 0.74 | 0.34–1.60 | 0.439 | 0.76 | 0.43–1.34 | 0.345 |
Exposure | ||||||
Non-heterosexual | 1 | 1 | ||||
Heterosexual contact | 0.49 | 0.11–2.13 | 0.344 | 0.34 | 0.20–0.59 | <0.001 |
CDC category * | 0.589 | |||||
A | 1 | |||||
B | 1.21 | 0.57–2.57 | 0.623 | |||
C | 0.85 | 0.46–1.57 | 0.613 | |||
Subtype | ||||||
Non CRF01_AE | 1 | 1 | ||||
CRF01_AE | 0.68 | 0.31–1.50 | 0.344 | 0.57 | 0.32–1.03 | 0.064 |
CD4, cells/mm3 | 0.394 | 0.824 | ||||
≤200 | 1 | 1 | ||||
≥201 | 2.54 | 0.33–19.74 | 0.373 | 0.86 | 0.49–1.66 | 0.663 |
Missing | 3.06 | 0.45–28.50 | 0.225 | 0.62 | 0.08–4.59 | 0.636 |
HIV RNA, copies/mL | 0.560 | 0.508 | ||||
≤50,000 | 1 | 1 | ||||
50,001–250,000 | 0.28 | 0.06–1.30 | 0.105 | 0.75 | 0.40–1.41 | 0.377 |
≥250,001 | 1.86 | 0.66–5.26 | 0.243 | 0.80 | 0.38–1.68 | 0.551 |
Missing | 2.03 | 0.81–5.11 | 0.131 | 2.00 | 0.24–16.53 | 0.518 |
HBsAg serostatus * | 0.226 | |||||
Negative | 1 | |||||
Positive | 1.88 | 0.89–3.98 | 0.096 | |||
Missing | 0.90 | 0.35–2.32 | 0.827 | |||
Anti-HCV serostatus * | 0.473 | |||||
Negative | 1 | |||||
Positive | 1.10 | 0.38–3.15 | 0.856 | |||
Missing | 0.63 | 0.29–1.36 | 0.238 |
Abbreviations: HBsAg – hepatitis B surface antigen, anti-HCV – antibody to hepatitis C virus.
p-value is for test for trend (excluding missing values) for age groups, CDC category, and HIV RNA.