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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Ophthalmology. 2013 Mar 21;120(9):1880–1892. doi: 10.1016/j.ophtha.2013.02.007

Table 11.

Risk Estimates, By Specified Percentile, For AREDS Subjects Assigned Simplified Severity Scale 3 (Upper Panel) or 4 (Lower Panel) At Baseline. Tables Reveal The Spectrum Of Risk Values Contributed Primarily By Genetic Predisposition.

Risk Estimates for Simplified Severity Scale 3
Year 2 Year 5 Year 10
Very Low (5%)   4.1%   9.8% 22.3%
Low (20%)   6.9% 16.3% 35.3%
Moderate (50%) 12.0% 27.2& 53.9%
High (80%) 16.1% 35.4% 65.6%
Very High (95%) 23.0% 47.8% 79.6%
Risk Estimates for Simplified Severity Scale 4
Year 2 Year 5 Year 10
Very Low (5%)   5.6% 13.4% 29.6%
Low (20%) 10.4% 23.8% 48.6%
Moderate (50%) 16.9% 36.9% 67.6%
High (80%) 23.3% 48.3% 80.0%
Very High (95%) 30.8% 59.9% 89.3%

AREDS = Age-Related Eye Disease Study