Fig. 2.

Epigenetic mechanisms that could be involved in hyperhomocysteinemia-induced stroke. These mechanisms also control genes of homocysteine pathway that leads to hyperhomocysteinemia. SAM S-adenosylmethionine, SAH S-adenosylhomocysteine, ncRNA noncoding RNA, HAT histone acetyltransferase, HDAC histone deacetylase, miRNA microRNA, DNMT DNA methyltransferase, snRNA small nuclear RNA, lncRNA long noncoding RNA, snoRNA small nucleolar RNA, siRNA small interfering RNA, tRNA transfer RNA, rRNA ribosomal RNA, gRNA guide RNA