Table 1.

Genes involved in homocysteine metabolism pathway

Gene symbols	Names
AHCY	S-Adenosylhomocysteine hydrolase
AMD1	S-Adenosylmethionine decarboxylase 1
BHMT	Betaine-homocysteine methyltransferase
CBS	Cystathionine-beta-synthase
CHDH	Choline dehydrogenase
CTH	Cystathionase
DHFR	Dihydrofolate reductase
FOLR1	Folate receptor 1
GIF	Gastric intrinsic factor
MAT1a	Methionine adenosyltransferase I, alpha
MAT2a	Methionine adenosyltransferase I, alpha
MAT2b	Methionine adenosyltransferase II, beta
MTHFD1	Methylenetetrahydrofolate dehydrogenase 1
MTHFD2	Methylenetetrahydrofolate dehydrogenase 2
MTHFR	5,10-Methylenetetrahydrofolate dehydrogenase
MTR	5-Methyltetrahydrofolate-homocysteine methyltransferase
MTRR	5-Methyltetrahydrofolate-homocysteine methyltransferase reductase
NNMT	Nicotinamide N-methyltransferase
PON1	Paraoxonase 1
SHMT1	Serine hydroxymethyltransferase 1
SHMT2	Serine hydroxymethyltransferase 2
SLC19A1	Solute carrier family 19 member 1
TCN1	Transcobalamin I
TCN2	Transcobalamin II
TYMS	Thymidylate synthase