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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Obesity (Silver Spring). 2013 May;21(5):1031–1038. doi: 10.1002/oby.20077

Table 2.

Metabolic characteristics and adiposity of subjects based on quartile of sex hormone binding globulin: Mean (SE), median (IQR), or percent.

Lower ← Sex Hormone Binding Globulin Quartiles → Higher p-trend
Q1 Q2 Q3 Q4
SHBG (nmol/L) 18.79 (0.91) 35.83 (0.67) 54.02 (0.83) 90.91 (3.46) <0.001
Race (%White) 75 75 68 76 0.86
Age (Yrs) 50.96 (0.36) 51.32 (0.36) 50.48 (0.41) 50.84 (034) 0.45
Pre/early peri-MP (%) 60 55 68 57 0.53
BMI (kg/m2 ) 32.36 (0.80) 29.62 (0.80) 27.16 (0.85) 25.96 (0.60) <0.001
Waist (cm) 95.40 (1.75) 91.40 (1.92) 86.28 (2.17) 80.66 (0.44) <0.001
Waist: Hip Ratio 0.83 (0.01) 0.83 (0.01) 0.82 (0.01) 0.79 (0.01) <0.001
VAT (cm2) 150.15 (9.13) 129.05 (9.12) 109.80 (9.72) 78.71 (5.32) <0.001
SAT (cm2) 406.94 (19.71) 381.94 (20.03) 294.15 (19.22) 271.71 (17.29) <0.001
Liver Attenuation (HU) 53.25 (1.84) 59.03 (1.48) 59.48 (1.59) 61.96 (0.99) <0.001
Triglycerides (mmol/L) 1.36 (0.97–2.03) 1.14 (0.79–1.58) 1.10 (0.90–1.41) 1.07 (0.80–1.37) 0.0068
HDL cholesterol (mmol/L) 1.38 (0.05) 1.45 (0.04) 1.53 (0.05) 1.66 (0.06) <0.001
LDL cholesterol (mmol/L) 3.38 (0.13) 3.12 (0.11) 3.54 (0.14) 3.05 (0.10) 0.35
Systolic BP (mmHg) 115.47 (1.82) 116.34 (2.23) 111.15 (2.32) 110.67 (1.95) 0.014
Diastolic BP (mmHg) 72.59 (1.18) 74.72 (1.23) 71.56 (1.37) 69.37 (0.96) 0.011
Glucose (mmol/L) 5.11 (4.61–5.55) 4.83 (4.50–5.05) 4.83 (4.55–5.22) 4.33 (4.66–4.88) <0.001
Insulin (pmol/L) 79.2 (55.6–120) 62.5 (50.7–87.5) 56.6 (47.2–72.2) 45.8 (36.1–63.2) <0.001
HOMA index 2.52 (1.67–4.83) 1.93 (1.55–2.61) 1.72 (1.42–2.29) 1.41 (1.09–1.81) <0.001
CRP (ng/mL) 5.69 (0.83) 4.12 (0.60) 3.02 (0.50) 2.65 (0.43) <0.001
Estradiol (pg/mL) 22.25 (13.85–43.15) 27.57 (14.55–53.15) 54.47 (17.05–98.05) 50.9 (39.95–109.10) <0.001
FSH (mIU/mL) 59.77 (6.43) 56.69 (6.65) 47.41 (7.02) 49.28 (5.15) 0.19
DHEAS (μg/dL) 126.94 (8.86) 132.45 (10.32) 106.83 (8.88) 119.66 (8.52) 0.35
Testosterone (ng/dL) 33.00 (1.57) 36.18 (2.48) 27.87 (1.80) 35.00 (2.32) 0.58

MP = menopausal