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. Author manuscript; available in PMC: 2013 Jun 28.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2011 Dec 6;1(1):40–51. doi: 10.1002/wdev.21

FIGURE 2.

FIGURE 2

Focused and dispersed modes of transcription initiation. In focused transcription, there is either a single predominant transcription start site or a cluster of start sites in a small region of several nucleotides. In dispersed transcription, there are multiple weak start sites that are distributed over a larger region of about 50 to 100 nucleotides. Focused promoters are generally associated with regulated genes, whereas dispersed promoters are typically found in housekeeping genes, which maintain steady levels of transcription.