Table 7.
Mean (Std Dev) of PODCI Parent Proxy Responses by Clinical Severity Groups for DMD Subjects
| Group | n | U. Extremity | Transfers | Sports | Pain | Happiness | Global | |
|---|---|---|---|---|---|---|---|---|
| Vignos Grade | ||||||||
| class 1 | 1 | 10 | 78 (14) | 88 (6) | 59 (14) | 76 (21) | 73 (27) | 75 (9) |
| class 2 | 2 | 31 | 78 (12) | 83 (12) | 58 (21) | 86 (16) | 83 (14) | 76 (11) |
| class 3–4 | 3 | 7 | 69 (20) | 59 (21)*** | 35 (24)^^ | 82 (20) | 74 (20) | 61 (18)*** |
| Knee Ext Strength | ||||||||
| >.8 N-m/kg | 1 | 10 | 78 (11) | 91 (7)* | 70 (21)^ | 85 (23) | 76 (30) | 81 (12)* |
| .4–.8 N-m/kg | 2 | 23 | 74 (15) | 78 (15) | 53 (17) | 80 (17) | 78 (15) | 71 (12) |
| <.4 N-m/kg | 3 | 13 | 78 (13) | 73 (16) | 40 (21) | 93 (9) | 82 (15) | 71 (10) |
| 10 Meter Walk | ||||||||
| <6 seconds | 1 | 23 | 81 (12) | 88 (7)* | 63 (17)^ | 79 (20) | 82 (21) | 78 (11) |
| 6–12 seconds | 2 | 17 | 71 (16) | 77 (15) | 51 (20) | 87 (14) | 79 (17) | 72 (12) |
| >12 seconds | 3 | 7 | 75 (9) | 68 (19) | 38 (25) | 92 (9) | 74 (17) | 68 (10) |
| Stand from Supine | ||||||||
| <5 seconds | 1 | 18 | 76 (13) | 86 (10) | 64 (19) | 81 (22) | 83 (21) | 77 (12) |
| 5–10 seconds | 2 | 14 | 80 (14) | 86 (8) | 61 (15) | 84 (15) | 83 (15) | 78 (8) |
| >10 seconds | 3 | 6 | 71 (18) | 71 (19)*** | 35 (16)*** | 88 (12) | 75 (18) | 66 (13) |
| Climb 4 Stairs | ||||||||
| <5 seconds | 1 | 24 | 79 (12) | 86 (10) | 64 (19)^ | 81 (20) | 81 (21) | 77 (12) |
| 5–10 seconds | 2 | 15 | 75 (14) | 86 (8) | 61 (15) | 89 (12) | 80 (18) | 78 (8) |
| >10 seconds | 3 | 7 | 73 (19) | 71 (19)*** | 35 (16) | 83 (14) | 78 (13) | 66 (13) |
| Gait Velocity | ||||||||
| >45 meters/min | 1 | 29 | 80 (12) | 88 (7)^ | 63 (17)+ | 82 (19) | 80 (19) | 78 (11)+ |
| 30–45 meters/min | 2 | 11 | 65 (15)** | 77 (15) | 51 (20) | 82 (13) | 83 (19) | 72 (12) |
| <30 meters/min | 3 | 4 | 84 (8) | 68 (18) | 38 (24) | 85 (21) | 76 (21) | 68 (10) |
Abbreviations: DMD, Duchenne muscular dystrophy; PODCI, Pediatric Outcomes Data Collection Instrument; Std Dev, standard deviation; U, upper.
*
Group 1 is significantly different from all other Groups.
**
Group 2 is significantly different from all other Groups.
***
Group 3 is significantly different from all other Groups.
+
Group 1 is significantly different from only Group 2.
^
Group 1 is significantly different from only Group 3.
^^
Group 2 is significantly different from only Group 3.