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(A) Principle of l-lysine sensor pSenLys. The transcriptional regulator LysG senses l-lysine (34) to naturally drive transcription of its target gene lysE. When this is fused to eyfp, cells exhibit fluorescence at an increased cytosolic l-lysine concentration. (B) lysC and murE are two targets known in C. glutamicum, which on specific mutations provoke an excess l-lysine synthesis.
