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MKL1 coordinates key epigenetic alterations on the ET-1 promoter. (A–G) HVECs were transfected with siMKL1 or SCR followed by exposure to 1% O2. ChIP assays were performed with anti-MKL1 (A), acetyl histone H3 (B) and H4 (C), methylated histone H3K4 (D, E, F) and H3K9 (G).
