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. 2013 Apr 24;41(12):6149–6160. doi: 10.1093/nar/gkt303

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Sample traces for DNA compaction observed in various topological states. (A) Nicked DNA. (B) Positively supercoiled DNA (ΔLk = +12). (C) Un-nicked DNA with ΔLk = 0. (D) Negatively supercoiled DNA (ΔLk = −15).