| Nucleoside reverse transcriptase inhibitors |
| Zidovudine |
Triphosphate derivatives |
| Stavudine |
Viral DNA integration |
| Lamivudine, Didanosine, Zalcitabine, Abacavir |
Termination of Viral DNA Synthesis |
| Non-nucleoside reverse transcriptase inhibitors |
| Nevirapine |
Viral DNA polymerase inhibition |
| Efavirenz, Delavirdine |
For inactivation of HIV-2 (hence some types are intrinsically resistant to NRTIs) |
| Protease inhibitors |
| Saquinavir, Ritonavir, Indinavir Nelfinavir, Amprenavir, Lopinavir |
Deactivate the HIV-1 protease by binding to the active site |
| Fusion inhibitors |
| Enfuvirtide |
Glycoprotein 41–dependent membrane fusion |
