Table 3.
Description of 34 VAD-related infections
| Event # |
Causative Organism(s) |
Description of VAD Infection* |
Device Type† |
Days on VAD support prior to infection |
|---|---|---|---|---|
| Gram-Positive | ||||
| 1 |
Staphylococcus epidermidis |
DL, PP, BSI | HM I | 36 |
| 2 | Coagulase-negative staphylococcus |
DL, BSI, PP | HM I | 8 |
| 3 | DL +/− BSI | HM I | 14 | |
| 4 | DL, PP, BSI | HM I | 22 | |
| 5 | DL, PP, BSI, septic emobli |
HM II | 15 | |
| 6 | PP | HM II | 20 | |
| 7 | DL | HM II | 102 | |
| 8 |
Staphylococcus aureus |
DL | HM I | 195 |
| 9 | DL, BSI, mycotic aneurysm with septic emboli and involvement of inflow/outflow tract |
HM I | 310 | |
| 10 | DL | HM II | 34 | |
| 11 | DL | HM II | 285 | |
| 12 | DL, PP, BSI | HM II | 177 | |
| 13 | DL | HM II | 120 | |
| 14 | DL, BSI | HM II | 42 | |
| 15 |
Enterococcus faecalis |
DL, PP, BSI | HM I | 68 |
| 16 | DL, SW, PP, BSI | HM I | 44 | |
| 17 |
E. faecalis and/or CoNS‡ |
PP, BSI +/− DL | HM I | 28 |
| 18 | E. faecium | PP, BSI | Ventrassist | 19 |
| 19 | Viridans streptococci | DL, SW, PP | HM II | 235 |
| Gram-Negative | ||||
| 20 |
Pseudomonas aeruginosa |
DL, PP, BSI, VAD pump housing outflow |
HM I | 16 |
| 21 | DL, SW, PP | HM II | 36 | |
| 22 | DL, BSI | HM II | 174 | |
| 23 |
P. aeruginosa +/− Pflourescens |
DL | HM I | 130 |
| 24 |
P. aeruginosa and Enterobacter aerogenes |
DL, PP | HM I | 206 |
| 25 |
Stenotrophomonas maltophilia |
DL | HM II | 237 |
| 26 | Escherichia coli | PP | HM II | 10 |
| 27 | Enterobacter cloacae | DL | HM II | 251 |
| 28 | Proteus mirabilis | DL | HM II | 242 |
| 29 |
Klebsiella pneumoniae and Morganella morganii |
SW, PP, BSI | HM I | 36 |
| 30 | Enterobacter, K. pneumoniae CoNS |
DL | HM II | 168 |
| 31 |
Yeast (Candida glabrata) |
DL, PP, BSI, eroded graft –->exsanguination |
HM I | 60 |
| 32 | Culture Negative | DL, PP | HM I | 86 |
| 33 | PP | HM II | 82 | |
| 34 | PP, outflow graft, inner device surface |
HM II | 65 |
DL, driveline; PP, pump pocket; SW, sternal wound; BSI, bloodstream infection.
HM I, Heartmate I®; HM II, Heartmate II®
Coagulase-negative staphylococcus (CoNS)