Table 3.
Meats (g/week)a | Type of breast cancer
|
||||||||
---|---|---|---|---|---|---|---|---|---|
Total
|
Premenopausal
|
Postmenopausal
|
|||||||
ncases | Person-years | MVRR (95 % CI) | ncases | Person-years | MVRR (95 % CI) | ncases | Person-years | MVRR (95 % CI) | |
Total meat | |||||||||
<400 | 229 | 100,331 | 1.00 (REF) | 103 | 64,221 | 1.00 (REF) | 103 | 25,443 | 1.00 (REF) |
400–599.9 | 262 | 110,340 | 1.02 (0.85–1.23) | 119 | 71,461 | 0.99 (0.75–1.29) | 110 | 26,730 | 1.01 (0.76–1.32) |
600–799.9 | 241 | 105,897 | 1.01 (0.83–1.22) | 102 | 70,534 | 0.85 (0.63–1.13) | 94 | 24,410 | 0.95 (0.71–1.28) |
800–999.9 | 198 | 82,818 | 1.08 (0.88–1.33) | 87 | 55,375 | 0.94 (0.69–1.28) | 79 | 18,611 | 1.05 (0.76–1.44) |
≥1,000 | 338 | 156,820 | 1.04 (0.85–1.28) | 162 | 107,936 | 0.94 (0.69–1.27) | 134 | 33,012 | 1.04 (0.76–1.42) |
ptrend | 0.60 | 0.64 | 0.75 | ||||||
Red meat | |||||||||
<100 | 492 | 197,620 | 1.00 (REF) | 203 | 124,977 | 1.00 (REF) | 223 | 51,235 | 1.00 (REF) |
100–199.9 | 335 | 141,125 | 1.00 (0.86–1.15) | 151 | 91,843 | 1.01 (0.83–1.22) | 140 | 34,124 | 0.96 (0.77–1.19) |
200–299.9 | 172 | 84,530 | 0.90 (0.75–1.09) | 75 | 57,437 | 0.90 (0.70–1.14) | 67 | 18,367 | 0.86 (0.65–1.15) |
300–399.9 | 102 | 49,674 | 0.95 (0.76–1.19) | 49 | 34,543 | 0.98 (0.73–1.31) | 38 | 10,036 | 0.92 (0.64–1.32) |
≥400 | 167 | 83,257 | 1.02 (0.83–1.24) | 95 | 60,727 | 1.01 (0.78–1.30) | 52 | 14,444 | 0.86 (0.62–1.20) |
ptrend | 0.83 | 0.89 | 0.39 | ||||||
Processed meat | |||||||||
<100 | 851 | 364,025 | 1.00 (REF) | 366 | 237,164 | 1.00 (REF) | 177 | 44,973 | 1.00 (REF) |
100–199.9 | 265 | 116,477 | 1.01 (0.87–1.17) | 130 | 78,958 | 1.16 (0.96–1.40) | 159 | 39,485 | 0.97 (0.77–1.22) |
≥200 | 152 | 75,704 | 0.99 (0.82–1.20) | 77 | 53,405 | 0.92 (0.72–1.18) | 184 | 43,748 | 0.93 (0.69–1.27) |
ptrend | 0.96 | 0.97 | 0.64 | ||||||
White meat | |||||||||
<100 | 225 | 96,243 | 1.00 (REF) | 104 | 62,246 | 1.00 (REF) | 97 | 23,951 | 1.00 (REF) |
100–199.9 | 268 | 124,886 | 0.92 (0.77–1.10) | 125 | 81,639 | 0.90 (0.71–1.13) | 105 | 29,725 | 0.89 (0.67–1.18) |
200–299.9 | 238 | 100,044 | 1.02 (0.84–1.23) | 110 | 66,692 | 1.02 (0.80–1.29) | 99 | 22,857 | 1.08 (0.81–1.44) |
300–399.9 | 143 | 66,033 | 0.90 (0.72–1.11) | 63 | 43,551 | 0.90 (0.67–1.20) | 61 | 15,689 | 0.95 (0.68–1.33) |
≥400 | 394 | 169,000 | 1.05 (0.87–1.25) | 171 | 115,399 | 0.90 (0.72–1.13) | 158 | 10,046 | 1.12 (0.85–1.47) |
ptrend | 0.45 | 0.47 | 0.25 | ||||||
Fish | |||||||||
<100 | 453 | 222,891 | 1.00 (REF) | 217 | 156,109 | 1.00 (REF) | 177 | 44,973 | 1.00 (REF) |
100–199.9 | 407 | 162,947 | 1.10 (0.95–1.26) | 179 | 105,715 | 1.05 (0.87–1.25) | 159 | 39,485 | 1.00 (0.80–1.25) |
≥200 | 408 | 170,368 | 1.03 (0.89–1.19) | 177 | 107,703 | 0.97 (0.80–1.17) | 184 | 43,748 | 1.04 (0.83–1.30) |
ptrend | 0.69 | 0.77 | 0.71 |
Multivariable relative risks (MVRRs) were adjusted for energy intake (quintiles), age at menarche (<12, 12–13, ≥14 years), body mass index (<25, 25–29, ≥30 kg/m2), family history of breast cancer (mother or sister), education (≤12, 13–15, ≥16 years), parity and age at first live birth (nulliparous, parity 1–2 and age at first birth <25 years, parity 1–2 and age at first birth 25–29 years, parity 1–2 and age at first birth ≥30 years, parity ≥3 and age at first birth <25 years, parity ≥3 and age at first birth 25–29 years, parity ≥3 and age at first birth ≥30 years), oral contraceptive use (yes/no), menopausal status (postmenopausal, premenopausal, and uncertain), age at menopause (<35, 35–39, 40–44, 45–49,50–54, ≥55 years), menopausal hormone use (yes/no), vigorous physical activity (none, ≤2, >2 h/week), smoking status (never, former, current), and alcohol intake (none, 1–3, 4–6, ≥7 drinks/week)
Red meat: 1 (3–6 oz) serving is equivalent to 85–143 g; processed meat: 1 (e.g., 1 oz, 1 slice, 1 hotdog) serving is equivalent to 20–45 g; white meat: 1 (4–6 oz) serving is equivalent to 112–140 g; and fish: 1 (3–5 oz) serving is equivalent to 98–112 g