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. Author manuscript; available in PMC: 2013 Jun 28.
Published in final edited form as: Biochem J. 2013 Jan 1;449(1):1–10. doi: 10.1042/BJ20121098

Figure 1. Integration of amino acid sensing with translational control.

Figure 1

Two signal transduction mechanisms are involved in sensing intracellular amino acids: GCN2 senses the absence of many amino acids and the TOR pathway senses the presence of particular amino acids. Both repress general translation and derepress translation of specific messages through distinct mechanisms.