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. Author manuscript; available in PMC: 2013 Jun 28.
Published in final edited form as: Biochem J. 2013 Jan 1;449(1):1–10. doi: 10.1042/BJ20121098

Figure 2. Model for amino acid sensing pathways in DR benefits.

Figure 2

Modulation of activity of GCN2 or TOR pathways by dietary or pharmacological interventions can lead to benefits. Not all interventions necessarily lead to all benefits. Broken lines indicate indirect or hypothesized effects; solid lines indicate known or direct effects. In some cases, yeast/mammalian gene names are both indicated respectively. AMPK, AMP-activated protein kinase.