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. Author manuscript; available in PMC: 2013 Jun 28.
Published in final edited form as: J Child Neurol. 2011 Jun 13;26(9):1145–1153. doi: 10.1177/0883073811408308

Figure 2.

Figure 2

Disturbances of cerebral microcirculation and blood-brain barrier permeabity 3 days after middle cerebral arterial occlusion. (A) ΔR2* time curves obtained before, during, and after a bolus of gadolinium-diethylenetriamine pentaacetic acid from the entire injured region of the ipsilateral hemisphere and a similar region in the contralateral hemisphere. (B) Representative images of ΔR2* (peak), time of contrast arrival relative cerebral blood volume transit time, and relative cerebral blood flow obtained in the same animal. (C) T1-weighted spin-echo images obtained 15 minutes after administration of 0.3 mmol/kg gadolinium-diethylenetriamine pentaacetic acid at the same slice locations as used for bolus response profiles. Two out of 3 pups exhibited contrast enhancement (arrows).